A Novel Ultrasound Finding for the Diagnosis of Giant Cell Arteritis: Comparison With Temporal Artery Biopsy Findings

Yusuke Kudo; Karin Hara; Michito Murayama; Sanae Kaga; Satomi Omotehara; Takahito Iwai; Masaru Kato; Utano Tomaru; Yoshihiro Matsuno; Akihiro Ishizu

doi:10.1002/jcu.23869

A Novel Ultrasound Finding for the Diagnosis of Giant Cell Arteritis: Comparison With Temporal Artery Biopsy Findings

Yusuke Kudo, Karin Hara, Michito Murayama, Sanae Kaga, Satomi Omotehara, Takahito Iwai, Masaru Kato, Utano Tomaru, Yoshihiro Matsuno, Akihiro Ishizu^*

^*Corresponding author for this work

Internal Medicine （1）

Research output: Contribution to journal › Article › peer-review

Abstract

Hypoechoic halo is a typical ultrasound finding in giant cell arteritis (GCA), but it may be a false positive due to arteriosclerosis. Therefore, we focused on the segmental distribution of GCA lesions, defined the luminal irregularity in long-axis images as the string of beads sign, and examined its diagnostic ability. As a result, the C-statistic of hypoechoic halo and string of beads sign was better than that of hypoechoic halo alone (1.00 vs. 0.89). Based on the above, the diagnostic ability of GCA can be improved by adding the string of beads sign to the conventional hypoechoic halo.

Original language	English
Pages (from-to)	359-363
Number of pages	5
Journal	Journal of Clinical Ultrasound
Volume	53
Issue number	2
DOIs	https://doi.org/10.1002/jcu.23869
State	Published - 2025/02

Keywords

giant cell arteritis
hypoechoic halo
temporal artery
ultrasound

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.1002/jcu.23869

Cite this

@article{48cda07ac844403c88488bef5422e5bf,

title = "A Novel Ultrasound Finding for the Diagnosis of Giant Cell Arteritis: Comparison With Temporal Artery Biopsy Findings",

abstract = "Hypoechoic halo is a typical ultrasound finding in giant cell arteritis (GCA), but it may be a false positive due to arteriosclerosis. Therefore, we focused on the segmental distribution of GCA lesions, defined the luminal irregularity in long-axis images as the string of beads sign, and examined its diagnostic ability. As a result, the C-statistic of hypoechoic halo and string of beads sign was better than that of hypoechoic halo alone (1.00 vs. 0.89). Based on the above, the diagnostic ability of GCA can be improved by adding the string of beads sign to the conventional hypoechoic halo.",

keywords = "giant cell arteritis, hypoechoic halo, temporal artery, ultrasound",

author = "Yusuke Kudo and Karin Hara and Michito Murayama and Sanae Kaga and Satomi Omotehara and Takahito Iwai and Masaru Kato and Utano Tomaru and Yoshihiro Matsuno and Akihiro Ishizu",

note = "Publisher Copyright: {\textcopyright} 2024 Wiley Periodicals LLC.",

year = "2025",

month = feb,

doi = "10.1002/jcu.23869",

language = "英語",

volume = "53",

pages = "359--363",

journal = "Journal of Clinical Ultrasound",

issn = "0091-2751",

publisher = "John Wiley & Sons Inc.",

number = "2",

}

TY - JOUR

T1 - A Novel Ultrasound Finding for the Diagnosis of Giant Cell Arteritis

T2 - Comparison With Temporal Artery Biopsy Findings

AU - Kudo, Yusuke

AU - Hara, Karin

AU - Murayama, Michito

AU - Kaga, Sanae

AU - Omotehara, Satomi

AU - Iwai, Takahito

AU - Kato, Masaru

AU - Tomaru, Utano

AU - Matsuno, Yoshihiro

AU - Ishizu, Akihiro

PY - 2025/2

Y1 - 2025/2

N2 - Hypoechoic halo is a typical ultrasound finding in giant cell arteritis (GCA), but it may be a false positive due to arteriosclerosis. Therefore, we focused on the segmental distribution of GCA lesions, defined the luminal irregularity in long-axis images as the string of beads sign, and examined its diagnostic ability. As a result, the C-statistic of hypoechoic halo and string of beads sign was better than that of hypoechoic halo alone (1.00 vs. 0.89). Based on the above, the diagnostic ability of GCA can be improved by adding the string of beads sign to the conventional hypoechoic halo.

AB - Hypoechoic halo is a typical ultrasound finding in giant cell arteritis (GCA), but it may be a false positive due to arteriosclerosis. Therefore, we focused on the segmental distribution of GCA lesions, defined the luminal irregularity in long-axis images as the string of beads sign, and examined its diagnostic ability. As a result, the C-statistic of hypoechoic halo and string of beads sign was better than that of hypoechoic halo alone (1.00 vs. 0.89). Based on the above, the diagnostic ability of GCA can be improved by adding the string of beads sign to the conventional hypoechoic halo.

KW - giant cell arteritis

KW - hypoechoic halo

KW - temporal artery

KW - ultrasound

UR - http://www.scopus.com/inward/record.url?scp=85206096813&partnerID=8YFLogxK

U2 - 10.1002/jcu.23869

DO - 10.1002/jcu.23869

M3 - 学術論文

C2 - 39394890

AN - SCOPUS:85206096813

SN - 0091-2751

VL - 53

SP - 359

EP - 363

JO - Journal of Clinical Ultrasound

JF - Journal of Clinical Ultrasound

IS - 2