Projects per year
Personal profile
Campus career
和漢医薬学総合研究所 教授 2017/04/01-2019/09/30
薬学・和漢系 教授 2019/10/01-
和漢医薬学総合研究所 教授 2019/10/01-
Research interests
1)NK細胞のバイオロジーと腫瘍免疫応答における役割
2)がん病態進展における腫瘍微小環境での自然免疫応答の役割
3)がんモデルにおける病態のリアルタイムイメージング
4) 和漢薬による免疫疾患制御
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Fields, Keywords
- Cancer
- Immunology
- Inflammation
- metastasis
- Host defenses
- Natural Killer cell
Field of expertise (Grants-in-aid for Scientific Research classification)
- Oncology
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Research on the role of tissue-resident NK cells in cancer immune-surveillance
Hayakawa, Y. (PI)
2021/04/01 → 2025/03/31
Project: Research
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Role of tissue-resident NK cells in tumor immune surveillance and their functional regulation
Hayakawa, Y. (Principal Investigator) & 田井中一貴 (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2021/04/01 → 2025/03/31
Project: Research Project
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the effects of CD206-positive macrophages on obesity-associated liver tumors
Usui, I. (PI), Nakagawa, T. (CoPI) & Hayakawa, Y. (CoI)
2016/04/01 → 2019/03/31
Project: Research
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Characterization of anti-asialo-GM1 monoclonal antibody
He, K., Kimura, T., Takeda, K. & Hayakawa, Y., 2025/01, In: Biochemical and Biophysical Research Communications. 743, 151197.Research output: Contribution to journal › Article › peer-review
Open Access -
CAMSAP2 enhances lung cancer cell metastasis by mediating RASAL2 degradation
Singharajkomron, N., Yodsurang, V., Limprasutr, V., Wattanathamsan, O., Iksen, I., Hayakawa, Y. & Pongrakhananon, V., 2024/02/01, In: Life Sciences. 338, 122391.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
CAMSAP3-mediated regulation of HMGB1 acetylation and subcellular localization in lung cancer cells: Implications for cell death modulation
Singharajkomron, N., Seephan, S., Iksen, I., Chantaravisoot, N., Wongkongkathep, P., Hayakawa, Y. & Pongrakhananon, V., 2024/06, In: BBA - General Subjects. 1868, 6, 130614.Research output: Contribution to journal › Article › peer-review
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Correction to: IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting (Nature Communications, (2017), 8, 1, (14607), 10.1038/ncomms14607)
Takeda, K., Nakayama, M., Hayakawa, Y., Kojima, Y., Ikeda, H., Imai, N., Ogasawara, K., Okumura, K., Thomas, D. M. & Smyth, M. J., 2024/12, In: Nature Communications. 15, 1, 10558.Research output: Contribution to journal › Comment/debate
Open Access -
Corrigendum to “CAMSAP3-mediated regulation of HMGB1 acetylation and subcellular localization in lung cancer cells: Implications for cell death modulation”. [BBA - General Subjects (2024) 1868: 130614] (BBA - General Subjects (2024) 1868(6), (S0304416524000576), (10.1016/j.bbagen.2024.130614))
Singharajkomron, N., Seephan, S., Iksen, I., Chantaravisoot, N., Wongkongkathep, P., Hayakawa, Y. & Pongrakhananon, V., 2024/08, In: BBA - General Subjects. 1868, 8, 130644.Research output: Contribution to journal › Comment/debate
Datasets
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Additional file 2 of Anti-inflammatory effects of Morus alba Linne bark on the activation of toll-like receptors and imiquimod-induced ear edema in mice
Umeyama, L. (Creator), Hardianti, B. (Contributor), Kasahara, S. (Creator), Dibwe, D. F. (Contributor), Awale, S. (Creator), Yokoyama, S. (Creator) & Hayakawa, Y. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.14396845.v1, https://springernature.figshare.com/articles/presentation/Additional_file_2_of_Anti-inflammatory_effects_of_Morus_alba_Linne_bark_on_the_activation_of_toll-like_receptors_and_imiquimod-induced_ear_edema_in_mice/14396845/1
Dataset
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Anti-inflammatory effects of Morus alba Linne bark on the activation of toll-like receptors and imiquimod-induced ear edema in mice
Umeyama, L. (Creator), Hardianti, B. (Contributor), Kasahara, S. (Creator), Dibwe, D. F. (Contributor), Awale, S. (Creator), Yokoyama, S. (Creator) & Hayakawa, Y. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5371306, https://springernature.figshare.com/collections/Anti-inflammatory_effects_of_Morus_alba_Linne_bark_on_the_activation_of_toll-like_receptors_and_imiquimod-induced_ear_edema_in_mice/5371306
Dataset
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SARS-CoV-2 spike RBD in complex with neutralizing antibody UT28K
Ozawa, T. (Contributor), Tani, H. (Contributor), Anraku, Y. (Contributor), Kita, S. (Contributor), Igarashi, E. (Contributor), Saga, Y. (Contributor), Inasaki, N. (Contributor), Kawasuji, H. (Contributor), Yamada, H. (Contributor), Sasaki, S.-I. (Contributor), Somekawa, M. (Contributor), Sasaki, J. (Contributor), Hayakawa, Y. (Contributor), Yamamoto, Y. (Contributor), Morinaga, Y. (Contributor), Kurosawa, N. (Contributor), Isobe, M. (Contributor), Fukuhara, H. (Contributor), Maenaka, K. (Contributor), Hashiguchi, T. (Contributor), Kishi, H. (Contributor), Kitajima, I. (Contributor), Saito, S. (Contributor) & Niimi, H. (Contributor), Protein Data Bank (PDB), 2022/05/25
DOI: 10.2210/pdb7X7O/pdb, https://www.wwpdb.org/pdb?id=pdb_00007x7o
Dataset
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Anti-inflammatory effects of Morus alba Linne bark on the activation of toll-like receptors and imiquimod-induced ear edema in mice
Umeyama, L. (Creator), Hardianti, B. (Contributor), Kasahara, S. (Creator), Dibwe, D. F. (Contributor), Awale, S. (Creator), Yokoyama, S. (Creator) & Hayakawa, Y. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5371306.v1, https://springernature.figshare.com/collections/Anti-inflammatory_effects_of_Morus_alba_Linne_bark_on_the_activation_of_toll-like_receptors_and_imiquimod-induced_ear_edema_in_mice/5371306/1
Dataset
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Additional file 2 of Anti-inflammatory effects of Morus alba Linne bark on the activation of toll-like receptors and imiquimod-induced ear edema in mice
Umeyama, L. (Creator), Hardianti, B. (Contributor), Kasahara, S. (Creator), Dibwe, D. F. (Contributor), Awale, S. (Creator), Yokoyama, S. (Creator) & Hayakawa, Y. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.14396845, https://springernature.figshare.com/articles/presentation/Additional_file_2_of_Anti-inflammatory_effects_of_Morus_alba_Linne_bark_on_the_activation_of_toll-like_receptors_and_imiquimod-induced_ear_edema_in_mice/14396845
Dataset
Prizes
Activities
- 27 Oral presentation
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Resveratrol induces apoptosis in melanoma cells via downregulation of survivin expression.
Hayakawa, Y. (Speaker)
2013/10/03 → 2013/10/05Activity: Talk or presentation › Oral presentation
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Identification of plant extracts sensitizing breast cancer cells to TRAIL
Hayakawa, Y. (Speaker)
2013/10/03 → 2013/10/05Activity: Talk or presentation › Oral presentation
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Role of inflammatory microenvironment for acquiring malignant phenotypes in QR32 fibrosarcoma model
Hayakawa, Y. (Speaker)
2013/10/03 → 2013/10/05Activity: Talk or presentation › Oral presentation
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Role of cross- talk between host immune responses and cancer cells in metastasis disease
Hayakawa, Y. (Speaker)
2013/10/03 → 2013/10/05Activity: Talk or presentation › Oral presentation
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Mesenchymal-transitioned cancer cells instigate surrounding cancer cells to metastasis via secretion of WNT ligands
Hayakawa, Y. (Speaker)
2013/10/03 → 2013/10/05Activity: Talk or presentation › Oral presentation
Courses
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応用和漢医薬学特論
Watanabe, S., Tohda, C., Morita, H., Hayakawa, Y., Awale, S., Nakagawa, Y., Kim, J. & Oku, M. 2024/12/04 → 2025/03/31
Course
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医薬品薬効動態学実習
Hosoya, K.-I., Tabuchi, A., Nitta, A., Sasaoka, T., Hashimoto, Y., To, H., Akanuma, S.-I., So, T., Kume, T., Sakurai, H., Watanabe, S., Shibahara, N., Tohda, C., Koizumi, K., Hayakawa, Y., Nakagawa, Y. & Kim, J. 2024/10/01 → 2025/03/31
Course
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医薬品薬効動態学実習
Hosoya, K.-I., Tabuchi, A., Nitta, A., Sasaoka, T., Hashimoto, Y., To, H., Akanuma, S.-I., So, T., Kume, T., Sakurai, H., Watanabe, S., Shibahara, N., Tohda, C., Koizumi, K., Hayakawa, Y., Nakagawa, Y. & Kim, J. 2024/10/01 → 2025/03/31
Course
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国際医薬学特論
Hosoya, K.-I., Tomohiro, T., Sakai, H., Tabuchi, A., Hirose, Y., Nitta, A., Matsuya, Y., Shimizu, T., Chiba, J., Fujii, T., Kume, T., Tohda, C., Koizumi, K., Morita, H., Hayakawa, Y., Awale, S. & Nakagawa, Y. 2024/10/01 → 2025/03/31
Course
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国際医薬学特論
Hosoya, K.-I., Tomohiro, T., Sakai, H., Tabuchi, A., Hirose, Y., Nitta, A., Matsuya, Y., Shimizu, T., Chiba, J., Fujii, T., Kume, T., Tohda, C., Koizumi, K., Morita, H., Hayakawa, Y., Awale, S. & Nakagawa, Y. 2024/10/01 → 2025/03/31
Course