Kazuto Shibuya - University of Toyama

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Research activity per year

Campus career

附属病院　助教　2012/04/01-2016/03/31
医学科　助教　2016/04/01-2019/09/30
分子病態医学系　助教　2016/04/01-2019/09/30
医学系　助教　2019/10/01-
医学科　助教　2019/10/01-
医学部医学科　基幹教員
学部運営への参画状況・・・有-医学科医学教育推進専門委員会
担当授業科目に係る状況・・・主要授業科目担当

Research interests

Na+,K+-ATPaseは原形質膜に存在し,細胞の膜電位を保つ重要なタンパク質である.このATPaseは,αおよびβサブユニットで構成され,αサブユニット(αNaK)にはα1からα4までのアイソフォームがある.ヒト肝細胞癌(HCC)ではαNaKとの関連についての報告はなく,本研究はHCCにおけるαNaKの発現変動および生理機能を明らかにすることを目的とした.その結果,HCCにおいてα3NaKは癌細胞の生存に寄与し,また治療のターゲットタンパク質になり得ると考えられた.

Research Fields, Keywords

gastroenterological surgery

Field of expertise (Grants-in-aid for Scientific Research classification)

Digestive surgery

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1 Similar Profiles

1 Finished

Study of searching of the new molecular target of the hepatocellular carcinoma overexpression of Na+,K+-ATPase
Shibuya, K. (PI)
2013/04/01 → 2015/03/31
Project: Research

70 Article
1 Comment/debate
1 Review article

A case of MSI-high pancreatic body-tail cancer successfully treated with radical resection after pembrolizumab
Ito, M., Watanabe, T., Oga, Y., Matsumoto, S., Kimura, N., Nagamori, M., Tanaka, H., Shibuya, K., Yoshioka, I. & Fujii, T., 2025/02, In: Clinical Journal of Gastroenterology. 18, 1, p. 208-213 6 p.
Research output: Contribution to journal › Article › peer-review
A case of successful conversion surgery for unresectable gallbladder cancer treated with durvalumab in combination with gemcitabine plus cisplatin
Araki, T., Muranushi, R., Takagi, K., Tanaka, H., Shibuya, K., Ando, T., Yoshioka, I., Hirabayashi, K., Yasuda, I. & Fujii, T., 2025/02, In: Clinical Journal of Gastroenterology. 18, 1, p. 161-168 8 p.
Research output: Contribution to journal › Article › peer-review
Conversion Surgery for Pancreatic Cancer
Horikawa, M., Fukasawa, M., Machi, J., Urushihara, H., Furuhara, Y., Sunakawa, A., Yamamoto, K., Kusunoki, H., Kimura, N., Muranushi, R., Shirai, Y., Hirano, K., Watanabe, T., Shibuya, K., Yoshioka, I. & Fujii, T., 2025/01/01, In: Japanese Journal of Cancer and Chemotherapy. 52, 1, p. 19-24 6 p.
Research output: Contribution to journal › Article › peer-review
A case of BRCA1-mutated giant pancreatic acinar cell carcinoma successfully treated with modified FOLFIRINOX therapy and radical resection
Watanabe, T., Nagaoka, Y., Kimura, N., Fukasawa, M., Shirai, Y., Hirano, K., Shibuya, K., Yoshioka, I., Hamashima, T. & Fujii, T., 2024/10, In: Clinical Journal of Gastroenterology. 17, 5, p. 970-975 6 p.
Research output: Contribution to journal › Article › peer-review
A multi-institutional randomized phase III study comparing minimally invasive distal pancreatectomy versus open distal pancreatectomy for pancreatic cancer; Japan Clinical Oncology Group study JCOG2202 (LAPAN study)
Ikenaga, N., Hashimoto, T., Mizusawa, J., Kitabayashi, R., Sano, Y., Fukuda, H., Nakata, K., Shibuya, K., Kitahata, Y., Takada, M., Kamei, K., Kurahara, H., Ban, D., Kobayashi, S., Nagano, H., Imamura, H., Unno, M., Takahashi, A., Yagi, S. & Wada, H. & 7 others, Shirakawa, H., Yamamoto, N., Hirono, S., Gotohda, N., Hatano, E., Nakamura, M. & Ueno, M., 2024/12, In: BMC Cancer. 24, 1, 231.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations

The efficacy of polyglycolic acid felt reinforcement in preventing postoperative pancreatic fistula after pancreaticojejunostomy in patients with main pancreatic duct less than 3â mm in diameter and soft pancreas undergoing pancreatoduodenectomy (PLANET-PJ trial): study protocol for a multicentre randomized phase III trial in Japan and Korea
Shibuya, K. (Creator), Jang, J.-Y. (Creator), Satoi, S. (Creator), Sho, M. (Creator), Yamada, S. (Creator), Kawai, M. (Creator), Kim, H. (Creator), Kim, S. C. (Creator), Heo, J. S. (Creator), Yoon, Y.-S. (Contributor), Park, J. S. (Creator), Hwang, H. K. (Creator), Yoshioka, I. (Contributor), Shimokawa, T. (Creator), Yamaue, H. (Creator) & Fujii, T. (Creator), figshare, 2019
DOI: 10.6084/m9.figshare.c.4614074, https://springernature.figshare.com/collections/The_efficacy_of_polyglycolic_acid_felt_reinforcement_in_preventing_postoperative_pancreatic_fistula_after_pancreaticojejunostomy_in_patients_with_main_pancreatic_duct_less_than_3_mm_in_diameter_and_soft_pancreas_undergoing_pancreatoduodenec/4614074
Dataset
The efficacy of polyglycolic acid felt reinforcement in preventing postoperative pancreatic fistula after pancreaticojejunostomy in patients with main pancreatic duct less than 3â mm in diameter and soft pancreas undergoing pancreatoduodenectomy (PLANET-PJ trial): study protocol for a multicentre randomized phase III trial in Japan and Korea
Shibuya, K. (Creator), Jang, J.-Y. (Creator), Satoi, S. (Creator), Sho, M. (Creator), Yamada, S. (Creator), Kawai, M. (Creator), Kim, H. (Creator), Kim, S. C. (Creator), Heo, J. S. (Creator), Yoon, Y.-S. (Contributor), Park, J. S. (Creator), Hwang, H. K. (Creator), Yoshioka, I. (Contributor), Shimokawa, T. (Creator), Yamaue, H. (Creator) & Fujii, T. (Creator), figshare, 2019
DOI: 10.6084/m9.figshare.c.4614074.v1, https://springernature.figshare.com/collections/The_efficacy_of_polyglycolic_acid_felt_reinforcement_in_preventing_postoperative_pancreatic_fistula_after_pancreaticojejunostomy_in_patients_with_main_pancreatic_duct_less_than_3_mm_in_diameter_and_soft_pancreas_undergoing_pancreatoduodenec/4614074/1
Dataset
Supplementary Material for: Role of Aquaporin-5 in Gallbladder Carcinoma
Sekine, S. (Creator), Shimada, Y. (Creator), Nagata, T. (Creator), Sawada, S. (Creator), Yoshioka, I. (Creator), Matsui, K. (Creator), Moriyama, M. (Creator), Omura, T. (Creator), Osawa, S. (Creator) & Shibuya, K. (Creator), Karger Publishers, 2013
DOI: 10.6084/m9.figshare.5125714, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Role_of_Aquaporin-5_in_Gallbladder_Carcinoma/5125714
Dataset
ISOlation Procedure vs. conventional procedure during Distal Pancreatectomy (ISOP-DP trial): study protocol for a randomized controlled trial
Okada, K.-I. (Creator), Kawai, M. (Creator), Hirono, S. (Creator), Sho, M. (Creator), Tani, M. (Creator), Matsumoto, I. (Creator), Yamada, S. (Creator), Amano, R. (Creator), Toyama, H. (Creator), Yamashita, Y.-I. (Creator), Gocho, T. (Creator), Shibuya, K. (Creator), Nagai, M. (Creator), Maehira, H. (Creator), Kamei, K. (Creator), Ohira, G. (Creator), Shirai, Y. (Creator), Takami, H. (Creator), Kimura, N. (Creator), Fukumoto, T. (Creator), Baba, H. (Creator), Kodera, Y. (Creator), Nakao, A. (Creator), Shimokawa, T. (Creator), Katsuda, M. (Creator) & Yamaue, H. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5622608, https://springernature.figshare.com/collections/ISOlation_Procedure_vs_conventional_procedure_during_Distal_Pancreatectomy_ISOP-DP_trial_study_protocol_for_a_randomized_controlled_trial/5622608
Dataset
Supplementary Material for: Role of Aquaporin-5 in Gallbladder Carcinoma
Sekine, S. (Creator), Shimada, Y. (Creator), Nagata, T. (Creator), Sawada, S. (Creator), Yoshioka, I. (Creator), Matsui, K. (Creator), Moriyama, M. (Creator), Omura, T. (Creator), Osawa, S. (Creator) & Shibuya, K. (Creator), Karger Publishers, 2013
DOI: 10.6084/m9.figshare.5125714.v1, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Role_of_Aquaporin-5_in_Gallbladder_Carcinoma/5125714/1
Dataset

International Society of the Study of the Lumbar Spine, Best presentation award（共著）
Shibuya, K. (Recipient), 2010/10
Prize
優秀ポスター賞
Shibuya, K. (Recipient), 2010/09/11
Prize
JOA-AAOS Exchange Traveling Fellow
Shibuya, K. (Recipient), 2006/01
Prize
とやま賞
Shibuya, K. (Recipient), 2006/05
Prize
Cervical Spine Research Society, Clinical Award（共著）
Shibuya, K. (Recipient), 2005/01
Prize

消化器疾患

Takahara, T., Kajiura, S., Minemura, M., Fujinami, H., Yoshioka, I., Shibuya, K., Hirano, K., Tajiri, K., Fujii, T., Yasuda, I., Okabe, M., Ando, T., Naruto, N., Miwa, T., Watanabe, T. & Shimada, S.

2024/10/01 → 2025/03/31

Course

内分泌・栄養・代謝・乳房

Tobe, K., Ishiki, M., Yoshioka, I., Okuno, N., Shibuya, K., Kitamura, H., Matsui, K., Fujii, T., Saitoh, J.-I., Chujo, D., Satake, T., Yanagisawa, S., Fujisaka, S. & Watanabe, T.

2024/04/01 → 2024/09/30

Course

第二外科
Sekine, S., Yoshioka, I., Shibuya, K., Hirano, K., Matsui, K., Fujii, T., Igarashi, T., Miwa, T., Watanabe, T. & Hashimoto, I.
2024/04/01 → 2025/03/31
Course
富山医療学
Inadera, H., Sekine, M., Inadera, H., Hayashi, A., Yoshimura, N., Tatsuse, T., Yamada, M., Nakashima, A., Minemura, M., Shibuya, K., Kinugawa, K. & Yasuda, I.
2023/10/01 → 2024/03/31
Course

消化器疾患

Minemura, M., Fujinami, H., Yoshioka, I., Shibuya, K., Hirano, K., Motoo, I., Tajiri, K., Fujii, T., Yasuda, I., Okabe, M., Ando, T., Naruto, N., Miwa, T., Watanabe, T., Hirabayashi, K., Hashimoto, I. & Watanabe, K.

2023/10/01 → 2024/03/31

Course